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In 1965, a liquid derived from tree pulp made painkillers obsolete, then big pharma buried it for 70 years. A bedridden patient at the University of Oregon with arthritis & joint pain that wouldn't respond to anything was walking in days. Not with pills, surgery or any treatment the doctors had seen before. He applied a clear liquid directly over their joints topically. Within minutes, it was measurable in the joint fluid. Within days, the pain vanished. They slept through the night for the first time in months, after years of arthritis. Patients who hadn't walked without pain in years were walking. So he tried it on more patients... and got the same results repeatedly. The researcher was Dr. Stanley Jacob. The liquid he used was an organic sulfur compound derived from tree pulp, called 'DMSO'. And he was stunned. Word spread fast through medical circles. By the early 1960s, physicians across the country were running the same experiment. They published findings in respected medical journals. The results were impossible to ignore. Chronic joint pain dropped. Morning stiffness that had lasted years cleared within weeks. Patients who had been told they needed joint replacement surgery cancelled their pre-ops. Surgeons used it. Arthritis patients used it. Athletes used it. Veterinarians packed it around the legs of racehorses after training. The New York Times covered it. 60 Minutes aired a segment. Patients were calling it a miracle. One researcher wrote at the time: "We don't fully understand every mechanism, but the results are undeniable. This compound reaches the joint directly. Nothing we have ever used has done that." ==== What Dr. Jacob and his colleagues uncovered next was something the medical establishment had no framework for. They had stumbled onto an entirely new category of treatment. A topical supplement. Ordinary oral supplements have to go through: ๐งช The stomach acid that destroys up to 60% before they enter the blood ๐ซ The liver processing raw materials before they can reach the joint ๐ด Dilution across 5 liters of blood ๐ค And then hope some negligible fraction finds its way to your joints. Meanwhile, topical supplements can be applied directly to the skin over the site that needed it. ==== So, what was the "topical supplement" DMSO provided? ๐ DMSO worked because DMSO is organic sulfur. It carried rich mineral sulfur directly into the joint tissue. Sulfur is the third most abundant mineral in the human body. It is the structural backbone of cartilage. It is the compound your joints use to retain water, maintain resilience, and repair damage. And in arthritic joints, it is consistently depleted to as little as one THIRD of the levels found in healthy, non-arthritic tissue. So surgeons used it. Arthritis patients used it. Athletes used it. Veterinarians used it on racehorses. The results were consistent enough that respected medical journals started publishing findings. The New York Times covered it. 60 Minutes aired a segment on it. Patients were calling it a miracle. The lesson? DMSO was a topical supplement - the richest topical supplement for joint-building sulfur available. That's why it worked. ==== Then suddenly... The research stopped. Not because it didn't work. It worked too well. And the wrong people noticed. The pharmaceutical industry had built a billion-dollar machine around patentable painkillers. Pills that managed symptoms. Drugs that kept patients coming back month after month, year after year. This compound was different. It was DMSO. Dimethyl sulfoxide. A natural byproduct of wood pulping, derived from tree pulp. Discovered almost by accident in a paper mill. And it was dirt cheap. Nobody could patent it. Nobody could own it. Nobody could make billions from it. So instead of developing it as a treatment, they buried it. Under the justification of eye damage in animal testing, after giving beagle dogs 100 to 500 times the dose that would ever be given to a human, the FDA halted all clinical use in 1965. Millions who had their lives changed lost their greatest source of relief overnight. DMSO disappeared from medical education. Erased from textbooks. Declared outdated and unscientific. Today it sits at Tractor Supply. Stamped "for veterinary use only", "not for human use" as horse liniment. While 125 countries, including Canada, Germany, Great Britain, and Japan - prescribe it openly for arthritis, joint & musculoskeletal pain. Those countries trained doctors to use it skilfully and carefully to achieve great results. And over 11,000 scientific articles have been published confirming its effects. But stateside, it was swept under the rug. ==== For two decades, the story largely disappeared from mainstream medicine. Then in the 1970s and 80s, a group of researchers started asking a quiet question. How do you make DMSO safe to reinstill public trust - with all the same benefits and pain-relieving properties? The answer was simple. DMSO is dimethyl sulfoxide. By adding a single oxygen atom, you get DMSOโ, now called MSM. Remember how DMSO was organically found from tree pulp? MSM is even better. It's found naturally in the human body and is a core building block of our mobility. Now, it's 10 times more stable. Non-reactive. With all the same joint-soothing benefits. Millions who heard of DMSO but were afraid, now had a topical supplement that could solve the root cause of joint pain. Those who used DMSO but didn't like the garlic stench, or risk of possible irritation if they used it wrong... Now, MSM offered all the benefits, with none of the risks. It even penetrated the skin and accumulated in the local tissue, without the indiscriminate carrying effect that made DMSO risky. Dr. Robert Herschler, one of the original DMSO researchers at Crown Zellerbach who had worked alongside Dr. Jacob in the early days, began investigating MSM as a therapeutic compound in the late 1970s. He filed some of the earliest patents on MSM for health applications. He had spent years watching what DMSO did in patients. And he believed MSM (DMSOโ) could deliver the same benefits in a form that was safe enough for everyday use. He was right. MSM began accumulating its own research base. Peer-reviewed studies on joint pain, cartilage health, inflammation reduction. Dr. Stanley Jacob published his own fully exhaustive research in "The Miracle of MSM" in 1999. ๐ฌ A randomised, double-blind, placebo-controlled trial published on PubMed confirmed it improved knee quality of life in patients with mild knee pain. ๐งช A Japanese research team confirmed it suppressed the cellular process that causes joint cells to die. ๐ข Its ability to inhibit inflammatory enzymes inside joint cells became one of the most documented mechanisms in topical joint research. MSM is the modern evolution of the age-old DMSO remedy, made safe. It is still the richest topical supplement for joint-building sulfur available - now with all the benefits and none of the drawbacks. ==== And then researchers asked the next question. If MSM can penetrate the skin and deliver sulfur directly into joint tissue, what else can it carry with it? This is where the story gets even more interesting. MSM penetrates the skin - but doesn't let everything else penetrate indiscriminately. This means combination therapies & remedies can be applied, without the same worry that made DMSO potentially irritating or dangerous. For joint health, this changes everything. ๐ Magnesium chloride, for instance. Arthritic joints are measurably depleted in magnesium as well as sulfur. Magnesium activates the enzymes responsible for cartilage repair. It is fantastic for relaxing muscles to promote sleep, which most who have OA struggle with. It restores the joint environment that inflammation has disrupted. ๐ต๏ธ Arnica montana, the mountainous European herb studied to match ibuprofen gel for topical pain reduction in knee and hand arthritis, disperses the swelling and soreness that builds around arthritic joints. That means pain relief without gut damage. Without the side effects that make long-term NSAID use so destructive. ๐ณ Frankincense essential oils too. They shut off the inflammatory signal at the source, and are aromatic and therapeutic for at-home, consistent joint relief. What started with DMSO proving that sulfur could be delivered transdermally into depleted joint tissue had evolved into something far more complete. ==== What happens if you use MSM with magnesium & other soothing botanicals for your joint pain? Most people notice the nights first. The 3am wake-up from the aching starts to settle within the first week. Not gone. But quieter. By week two the mornings change. The stiffness that used to take an hour to work through starts clearing in ten minutes. You start getting out of bed without the ritual. By month one the magnesium and MSM have had time to begin replenishing what years of depletion have taken. Because it's not just pain relief - remember, it's a topical supplement that replenishes the sulfur & magnesium stores in your body overtime. Morning stiffness is measurably reduced. Movement is less painful. Most people have already reduced their painkiller use without consciously trying. By month two flexibility improves. Sleep is consistently better. The joint that used to announce itself with every step is quieter. By month three, this is where it compounds. Three months of consistent mineral replenishment. Most people at this point have either significantly reduced or completely stopped their daily painkiller use. ==== What people are saying: "I was facing a cortisone injection every eight weeks just to walk. After two weeks on the cream my doctor cancelled the next one. My pain is gone. I'm back in the garden. It gave me my life back." โ David T., 64 "The throbbing in my hands was so bad I couldn't cook or knit. I thought I was heading for wrist fusion surgery. The cream eliminated the swelling. I feel 20 years younger." โ Margaret S., 59 "I was taking four Advil every morning. My doctor warned me about my liver. This cream is the only thing that actually melts the stiffness. I stopped the pills and I'm walking two miles a day." โ Linda P., 71 ==== How to use it? Apply a small amount directly over the affected joint morning and night. Ideally after a warm shower when your pores are most open and absorption is most efficient. Massage in until absorbed and let it air dry before dressing. Because it's a topical supplement, consistency is key to let it build up in your joints overtime. PS: If you're still using ibuprofen, taper slowly rather than stopping cold turkey. The cream works alongside whatever you're currently doing. ==== Don't buy everything separately from Amazon which'll cost you upwards of $50-60 every month. Outfield Organics Deep Sea Magnesium & MSM True Joint Cream contains even more soothing herbs like lavender, arnica & frankincense. Choose products that don't chuck the main ingredients at the bottom of the label. Find Dimethyl Sulfone (MSM) & Deep Sea Magnesium at the top. 90-day money-back guarantee. If nothing shifts, full refund, no questions asked. โ https://outfieldorganics.com/pages/adv2 P.S. Dr. Jacob, who started all of this at the University of Oregon in 1961, spent the rest of his career advocating for the therapeutic potential of transdermal MSM sulfur delivery.
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