LuxMixy ad creative
LuxMixy
LuxMixy

Active· since Sep 11, 2026

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I'm sixty-three and I've spent nineteen years taking Buscopan for IBS that comes back worse every single time the tablet wears off, and last April I left my son's wedding rehearsal dinner after the starter because I knew if I stayed seated for another ten minutes I'd have an accident at the table. Nobody saw me go. I told my son's fiancée I had to take a phone call. I sat in the car park for forty minutes until my stomach emptied, then drove home. I texted him: "Wasn't feeling great, sorry, see you Saturday." I didn't go on Saturday either. That was the night I typed "IBS nothing works" into Google at 1am. Again. The same search I've made every few months for nearly two decades. But that night I found something different. I should go back. My gut started playing up in 2007 after a course of antibiotics for a chest infection. Within six months I was going four, five times a day. Urgency that left me no margin. Cramping that hit twenty minutes after eating. The GP ran bloods, a stool test, eventually a colonoscopy. Everything normal. "Irritable bowel syndrome. Reduce stress." I tried low-FODMAP. My wife helped me follow it properly. Rice, steamed fish, no wheat, no onion. It helped for about three months and then the cramping came back and the diarrhoea never fully stopped. I abandoned it because I couldn't follow it at business lunches. I was still working then. Consulting. Clients didn't need to know my stomach was ruining my career. Then probiotics. Bio-Kult first, then Symprove. Twenty-one pounds a month for the first, forty-nine for the second. Each one gave me a fortnight of something like hope. Then back to baseline. I tried Alflorex after reading about it online. Same thing. Two good weeks. Nothing. Buscopan became my crutch. I carried it everywhere. Still do. It dulls the worst cramp for an hour or two. Then the cramp comes back. Every time. It's not fixing anything. It's buying me sixty minutes. Mebeverine from the GP. Two courses. Some initial help with the cramping. Then my body seemed to get used to it. Back to square one. Peppermint capsules. Helped the cramp a touch. Gave me acid reflux. Didn't touch the diarrhoea, the urgency, the bloating. I tried CBD capsules from a health shop in town. Six weeks. Felt absolutely nothing. Assumed it was another supplement that didn't work. Threw them away. I tried a mindfulness app because the GP suggested stress management after the second colonoscopy. I'm sixty-three years old. I ran projects that built bridges. I don't need a breathing exercise. I need my gut to stop punishing me every time I eat. My wife passed three years ago. Bowel cancer. The cruel irony is I live in terror of the same thing every time my gut flares badly. Every bad week I think, what if this time it's not just IBS. After she died, I stopped eating out. There was nobody to cover for me any more. Nobody to quietly explain I'd had to leave. I eat alone now. The same five meals she used to make. I make them the same way every time. It's all I trust. My life got smaller. Not because of the grief. Because of the gut. The grief made it lonely. The gut made it small. Not the pain. Not the cramping. The smallness. My late wife's friend, Diane, came for tea last autumn. She'd read an article about gut health. She said, "Have you heard of the gut-brain?" I hadn't. She sent me the link after she left. The article was written by a gastroenterologist who'd spent decades studying what goes wrong in functional gut disorders. He opened with a question nobody had ever asked me: "Has anyone ever explained what's actually happening inside your gut-brain?" Nobody had. Not in nineteen years. Your gut contains five hundred million nerve cells. More than your spinal cord. That figure comes from Furness (2006), who mapped the enteric nervous system across decades of research. This isn't a metaphor. It's a real nervous system running your digestion on its own, separate from your brain. That nervous system has dimmer switches. Receptors called CB1 and CB2. When they work, your gut squeezes at the right speed, at the right strength. You don't feel a thing. When they malfunction, the gut squeezes too hard. Pushes food through too fast. Or clamps down and holds everything. The nerve endings in the gut wall become so sensitive that normal stretching and gas, things a healthy person would never notice, register as pain. Two things go wrong at the same time. The dimmer switches jam on overdrive. And the gut wall inflammation makes every signal louder. Think of it like a dimmer switch wired to every light in your house, jammed all the way to the top. Every room is blinding. You can unscrew bulbs. You can tape over your eyes. But until someone gets into the wiring and unjams the switch, nothing changes. That's what hit me. Every treatment I'd tried in nineteen years was unscrewing bulbs. Probiotics changed the bacteria living in the gut. But the bacteria aren't controlling the squeezing. The gut-brain is. The bacteria are the tenants. The gut-brain is the landlord. I'd been swapping tenants for two decades while the landlord ran the building into the ground. Antispasmodics paralysed the gut muscle for an hour. Then the gut-brain turned the volume right back up. FODMAP took away the foods that triggered the loudest reactions. But the oversensitive gut-brain was still there. Still overreacting to everything else. Peppermint relaxed one layer. One. Temporarily. The protocol is the protocol. Nobody questioned it. Nobody was talking to the gut-brain itself. Nobody was resetting the dimmer switches. Mechanism. That one word reframed nineteen years. You need two things. Something that talks directly to the gut-brain's dimmer switches. And something that calms the inflammation making the gut wall too sensitive. At the same time. Through the blood, not through the broken gut. A study in the British Journal of Pharmacology (Izzo, 2012) found that a cannabinoid called CBC, cannabichromene, calmed an overactive gut back to normal speed in laboratory research without slowing a gut that was already working fine. Not CBD on its own. Not THC. CBC. The one most brands don't even know is in their product. And the CBD capsules I'd thrown away? They had to survive my stomach acid, get absorbed through a gut wall that doesn't absorb properly, then pass through my liver, which would have destroyed most of it. I'd swallowed the fix through the broken system. Of course it didn't work. Drops under the tongue enter the bloodstream in seconds. They don't touch the stomach. They don't pass through the damaged gut. They don't get destroyed by the liver. They go around the broken system entirely and reach the gut-brain through the blood. I didn't tell Diane I'd ordered them. I didn't tell anyone. I was too tired of hope dying in a fortnight. Night one. One dropper under my tongue before bed. Held it for sixty seconds. Went to sleep. Nothing remarkable. Morning. I noticed the familiar tightness before breakfast wasn't there. Small. Easy to dismiss. Week two. I ate a full plate at Sunday lunch for the first time in months. The cramping didn't come. I waited for it. It didn't come. Month one. The urgency that used to hit within an hour of eating had softened. I slept through the night five times that week. I'd been waking at 3am for years. Month three. I drove to my son's house for dinner. His wife made lasagne. I ate two helpings. I sat at their table for three hours. I didn't once think about where the toilet was. On the drive home, I realised I'd forgotten to take Buscopan. I hadn't forgotten. I just hadn't needed it. My son rang the next morning. He said, "Dad, you stayed for pudding. You never stay for pudding." He was right. If you carry Buscopan in your jacket pocket every time you leave the house. If you've mapped every service station on the motorway between your house and your son's. If you eat the same five meals because they're the only things you trust. If you've left a table, a meeting, a family event because your gut gave you no choice. If you lie awake at night wondering if it's getting worse and when it stops. Read the article I found. It explains what "The Overdriven Gut" really means, why the dimmer switches in your gut-brain get jammed, and why every capsule you ever swallowed went through the broken system instead of around it. I wish I'd found it nineteen years ago. https://www.willowmereqentharis.com/gutvora/gut

The 1 thing about IBS no GP mentioned — and why I eat every meal alone at 63

The probiotic industry earns millions from your cramps and bloating — while knowing that bacteria are not the cause of your bowel issues.

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