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Tretinoin also known as (Retin-a) is a vitamin A derivative and also a medicine, topically used to treat acne, melasma and minimize skin aging-signs such as wrinkles and fine lines by accelerating collagen production and encouraging cell turnover and regeneration process which in turn boost skin cell renewal for a healthier and brighter-looking skin. Tretinoin usually comes in 3 strengths – 0.025% – mildest-strength, 0.05% – medium-strength and 0.1% – strongest-strength. It's advice to start from the lowest so as to allow your skin to build tolerance to tretinoin before moving ahead slowly to higher strength