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⚠️ Did you know? Laminitis is not just a spring grass problem. Up to 90% of pasture-associated laminitis cases are linked to insulin resistance. Many horses develop laminitis because of Equine Metabolic Syndrome (EMS) or insulin dysregulation. ➡️ When a horse’s cells become resistant to insulin, blood sugar stays too high — triggering a hormonal cascade that weakens the sensitive laminae inside the hoof. This is the leading metabolic cause of founder. Some horses may be prescribed Metformin to help control blood insulin concentrations and to promote weight loss. Metformin is an oral prescription drug that’s widely used in human medicine to treat Type 2 diabetes. But…..DOES METFORMIN ACTUALLY WORK IN HORSES?!? Maybe not………. Evidence: Metformin in Horses 📚 Durham AE, Rendle DI, Newton JE (2008) • Dr. Andy Durham, a leading UK equine internal medicine veterinarian, looked at metformin’s use in EMS horses. • Findings: Metformin DID NOT consistently reduce blood insulin concentrations or improve insulin sensitivity. • It may help blunt glucose spikes if given right before a high-starch meal — but that’s not practical or effective for most forage-based diets. 📚 Frank N et al. (2009) • Dr. Nicholas Frank (a leading EMS/Cushing’s researcher) did a clinical study at the University of Tennessee. • Horses were given metformin for 21 days — the drug DID NOT significantly lower baseline insulin or improve insulin resistance. • It might help slightly reduce glucose absorption from the gut, but its oral bioavailability in horses is extremely low. ⚖️ Why it Fails • Horses absorb oral metformin very poorly — less than 10% makes it into circulation. • Unlike humans, horses eat a forage-based diet — they aren’t dealing with the same type of meal-driven glucose spikes that metformin targets. What are some NATURAL options? 🌱 - MAGNESIUM AND CHROMIUM! In the mid-2000s, Dr. Andy Durham ran field trials on horses with Equine Metabolic Syndrome (EMS) and chronic laminitis. - He found that adding magnesium and chromium to a strict low-NSC diet helped: ✅ Reduce resting insulin concentrations ✅ Improve how the cells respond to insulin ✅ Lower the risk of painful laminitis flare-ups 🌟 Metabo-Balance: A Research-Backed Natural Solution 🩺🔬 We’ve designed Metabo-Balance with research backed ingredients to help your horse battle EMS, insulin dysregulation, and laminitis risk: • Magnesium Citrate — not cheap oxide — gentler on the gut and more bioavailable for real cellular effect. • Chromium Propionate — a modern, organic form that works at the insulin receptor level. • Ceylon Cinnamon (Cinnamomum verum) — true cinnamon, naturally low in coumarin but rich in cinnamaldehyde and polyphenols that help support healthy glucose metabolism. • Fenugreek (Trigonella foenum-graecum) — a powerhouse seed rich in soluble fiber (galactomannan) and saponins, shown to slow carb absorption and help steady blood sugar. Plus, horses love the taste. This product was veterinarian designed to support your horse naturally and give you (as a concerned owner) another option besides medication - that may or may not be helpful. 🐴💗😊